NOLLMANN LAB
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    • DNA organization and segregation at super-resolution >
      • Chromosome structure
      • Resources and background
    • Molecular Motors >
      • SpoIIIE and FtsK
      • Bacterial gliding
    • Technologies >
      • SRM
      • SMLM microscope
    • Software
  • Lab members
    • Lab pictures
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Who we are

Who we are

Welcome to Marcelo Nollmann's research group at the Center for Structural Biochemistry of the CNRS/INSERM

We develop single-molecule and advanced microscopy methodologies to understand the mechanisms underlying DNA organization and transcription in multi-cellular organisms.

News

  • We are happy to present our latest work on 3DGenome organization and transcription during drosophila development, now available as a biorxivpreprint.
  • Want to know how phase-separated droplets are segregated in bacteria? See our new article in Molecular Cell! check out the biorxivpreprint and the paper in Molecular Cell. Voir aussi publication du CNRS.
  • Do you want to do Hi-M in your lab? Check out our VERY detailed protocol in Nature Protocols here.
  • Nov'19: Prix Etancelin de l'Academie des Sciences See here
  • Apr 19: Congratulations Jean-Bernard and Antoine for their papers appearing in Science and Nanoscale!
  • Feb 19: congratulations to the team for the Hi-M paper being accepted in Mol Cell !
  • Jan 18: physics to understand living systems: interview by the Bettencourt Schueller Fondation.

Featured Publications

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ATP-Driven Separation of Liquid Phase Condensates in Bacteria

Guilhas, et al, Mol Cell (2020)

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Microscopy-based chromosome conformation capture enables simultaneous visualization of genome organization and transcription in intact organisms
​Cardozo-Gizzi, et al. Mol Cell (2019)

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Direct and simultaneous observation of transcription and chromosome architecture in single cells with Hi-M.
​Cardozo-Gizzi, et al. Nature Protocols (2020)
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The mechanism of force transmission at bacterial focal adhesion complexes.
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Faure, et al. Nature (2016) [Blog] [Video]
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Single-cell absolute contact probability detection reveals that chromosomes are organized by multiple low-frequency yet specific interaction
Cattoni, et al. Nature Comm (2017)
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Bacterial partition complexes segregate within the volume of the nucleoid
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Le Gall, et al. Nature Comm (2016)
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Condensin- and replication-mediated dynamic folding of a bacterial chromosome and its origin domain revealed by super-resolution imaging/ Hi-C​
​Marbouty, Le Gall, et al. Mol Cell (2015)
A complete list of publications, including chapters and articles not accessed by PubMed, can be found here.

Funders

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  • Home
    • News
    • Lab meetings
  • Research
    • DNA organization and segregation at super-resolution >
      • Chromosome structure
      • Resources and background
    • Molecular Motors >
      • SpoIIIE and FtsK
      • Bacterial gliding
    • Technologies >
      • SRM
      • SMLM microscope
    • Software
  • Lab members
    • Lab pictures
  • Publications
  • Resources
  • Positions
  • Funding
  • Contact